Fitness for Health and Relaxation

U.S. researchers studying the effects of stress on the intestines unexpectedly found a chemical compound that stimulates hair growth.

By blocking a hormone linked to stress and hair loss, experts achieved in a group of mice genetically engineered to produce too much of this hormone to regenerate lost hair, a team reported in the online edition of the journal Plops One

“Almost 100% of the mice responded. The hair grew back completely. It is a very dramatic effect,” said Mulugeta Million, University of California at Los Angeles, who worked on the study.

Mulugeta said the findings could open new areas of exploration on hair loss in humans, especially those in which the disorder is related to stress and aging.

The team, which included experts from the Veterans Administration and the Salk Institute for Biological Studies in California, was conducting experiments with mice that had been genetically altered to produce an excessive amount of stress-related hormone called corticotrophin releasing factor (CRF for its acronym in English).

As these chronically stressed mice got older, his hair turned gray and finally fell. Mulugeta compared the effect observed with aging to see a U.S. president after the course of two terms of four years in the White House.

The team injected the mice to block the chemical stress called stressing-B “, which stops the action of CRF. The mice received daily injections for five days, then the team measured the effects of the drug on his colon and he replaced in their cages.

“When we returned three months later, his hair had grown back completely. I could not distinguish them from their peers who had not been genetically modified,” said Mulugeta. “It was totally unexpected,” he said.

The effect remained for four months, a relatively long time in the life of a mouse, said the author. Follow-up studies confirmed the findings.

The team also evaluated the compound in modified mice younger than even they had not lost his hair and found that stressing-B avoid becoming frayed.

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Tags: hair, stress, stress effects

This entry was posted on Thursday, February 17th, 2011 at 3:21 pm and is filed under stress effects. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.