At present, there is a high prevalence of erectile dysfunction or impotence in men with cardiovascular risk factors such as diabetes mellitus, hypertension, high blood cholesterol and smoking. Approximately 35 to 75% of men with diabetes mellitus suffering from erectile dysfunction. In addition, it is considered a sentinel symptom of sub clinical vascular disease or silent.
The state prior to the development of type 2 diabetes and metabolic syndrome is called is an emerging problem of great social impact, which is closely linked to obesity and can lead to cardiovascular disease.
The erection is a homodynamic process (a process that is involved in blood flow) complex that requires the physiological integrity of nerve pathways and blood vessels incarnation, in addition to foreplay. Ultimately is produced by the relaxation of penile arteries, as well as the expansion and blood filling the corpora cavernous of the penis. The arterial wall has an inner layer called the endothelium, that releases various substances both vasodilator and vasoconstrictor.
The enzyme cyclooxygenase (COX), inhibited by the group of drugs known as no steroidal anti-inflammatory drugs (NSAIDs) which includes aspirin, produces a series of mediators called prostanoids, implicated in inflammation, and homeostasis processes and regulation of tone vascular.
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Tags: blood vessels incarnation, both vasodilator and vasoconstrictor, cardiovascular, diabetes mellitus, erectile dysfunction, high blood cholesterol, homodynamic process, hypertension, impotence, metabolic syndrome, pathways
